New Drug which reverses Alzheimer's found


This is a major step in the treatment for Alzheimer as the new drug compound that has been found that turns the cognitive discrepancies of the disease.

Lead author Paul Lombroso and the co-authors studied thousands of small molecules in mice, searching for those that would inhibit STEP activity and found a reversal of deficits in several cognitive exercises that gauged the animals' ability to remember previously seen objects.

Lombroso said that the small molecule inhibitor was the result of a five-year collaborative effort to search for STEP inhibitors. A single dose of the drug resulted in improved cognitive function in mice. Animals treated with TC compound were indistinguishable from a control group in several cognitive tasks. Since this is still in the research state it would take some more time for the formulation to be tested on humans and to be produced commercially for treatment of Alzheimers’. The findings are published in the journal PLOS Biology.

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